Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 1.328


Transcription factors associated with POU5F1_SOX2{dimer}.p2:

Gene SymbolEntrez IDGene Name
Pou5f1 18999 POU domain, class 5, transcription factor 1
Sox2 20674 SRY-box containing gene 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou5f1chr17_+_35642981-0.063.9e-01Click!
Sox2chr3_+_34549057-0.019.3e-01Click!


Activity profile for motif POU5F1_SOX2{dimer}.p2.

activity profile for motif POU5F1_SOX2{dimer}.p2


Sorted Z-values histogram for motif POU5F1_SOX2{dimer}.p2

Sorted Z-values for motif POU5F1_SOX2{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1_SOX2{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_20676453 23.908 NM_013467
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr3_-_113280650 14.904 NM_001110505
Amy1
amylase 1, salivary
chr6_+_70676428 13.089


chr6_+_70676803 12.853


chr14_+_45119792 12.824 NM_198677
BC061237
cDNA sequence BC061237
chr7_+_23656242 12.642 NM_001166724
Vmn1r160
vomeronasal 1 receptor 160
chr17_-_25218117 12.441 Tmem204
transmembrane protein 204
chr16_+_35001358 11.360 Mylk
myosin, light polypeptide kinase
chr9_-_54509453 11.198 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_-_54509658 11.041 NM_053178
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr2_+_25036524 10.444 Nrarp
Notch-regulated ankyrin repeat protein
chr7_-_110962416 10.241 NM_008220
NM_016956
Hbb-b1
Hbb-b2
hemoglobin, beta adult major chain
hemoglobin, beta adult minor chain
chr7_+_147949637 9.928 Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr3_+_90346956 9.849 S100a16
S100 calcium binding protein A16
chr19_+_30020236 9.703 NM_001164724
Il33
interleukin 33
chr7_+_23307985 9.281 NM_001166738
NM_001166752
Vmn1r104
Vmn1r152
vomeronasal 1 receptor 104
vomeronasal 1 receptor 152
chr2_+_25036276 9.259 NM_025980
Nrarp
Notch-regulated ankyrin repeat protein
chr7_-_22331108 9.072 NM_001166839
NM_001167169
NM_001167168
NM_001166746
Gm4172
Gm4179
Gm4220
Vmn1r111
predicted gene 4172
predicted gene 4179
predicted gene 4220
vomeronasal 1 receptor 111
chr7_+_21119185 9.036 NM_001166738
NM_001166752
Vmn1r104
Vmn1r152
vomeronasal 1 receptor 104
vomeronasal 1 receptor 152
chr3_+_97432726 8.848 NM_001161763
NM_001161765
NM_010232
Fmo5


flavin containing monooxygenase 5



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
9.78 3.29e-02 GO:0042573 retinoic acid metabolic process
8.03 2.81e-02 GO:0006776 vitamin A metabolic process
7.53 3.13e-03 GO:0006721 terpenoid metabolic process
5.32 8.97e-03 GO:0019748 secondary metabolic process
5.23 4.07e-03 GO:0034754 cellular hormone metabolic process
3.97 8.62e-03 GO:0042445 hormone metabolic process
3.15 2.80e-02 GO:0010817 regulation of hormone levels
3.10 2.10e-02 GO:0008202 steroid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
1.96 4.31e-04 GO:0005624 membrane fraction
1.91 7.88e-04 GO:0005626 insoluble fraction
1.85 1.65e-04 GO:0000267 cell fraction

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
3.36 2.64e-02 GO:0004497 monooxygenase activity